Some drugs suppress saliva production, which will negatively impact your teeth. Others are stimulants that made you grind your teeth with nervous energy.
But it is also largely a lifestyle thing. If your money is going to drugs instead of food, housing, and dentistry, you whole body, teeth included, will suffer.
What they said plus people that go days on end on a bender don’t practice good hygiene. When you’re tweaked out for a days or weeks at a time you’re not likely to be brushing/ showering etc. You’re whole body takes damage/ gets dirty, but unlike your teeth, your body can repair much of it. Damage to your teeth is permanent. Damage to your skin/hair/nails isn’t.
Because different drugs have different effect on different tissues. Some metabolic products of some antibiotics get accumulated in bone and teeth tissue because those tissues have chemicals or physical characteristics that favor deposition of such substances. Some drugs affect physiology of teeth, mouth and/or blood supply to these, which changes the environment teeth grow/live in.
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