Your dead skin is *one thing that is in* dust. There are other things. Plant pollens can make up a large portion of the dust, even in your house.
Besides, feeding on that dead skin are a bunch of little tiny beasties, themselves alive and chemically active. And the, (ahem) products of their digestion are chemically active.
All of these things can be irritants in themselves, and/or things that you have an allergic reaction to.
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